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14-3-3 sigma/SFN antibody (Middle Region)

SFN Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN634143
  • Target See all 14-3-3 sigma/SFN (SFN) Antibodies
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Binding Specificity
    • 15
    • 13
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 103
    • 35
    • 28
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 93
    • 9
    • 2
    • 1
    Rabbit
    Clonality
    • 88
    • 17
    Polyclonal
    Conjugate
    • 48
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This 14-3-3 sigma/SFN antibody is un-conjugated
    Application
    • 86
    • 44
    • 38
    • 23
    • 17
    • 15
    • 14
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    SFN antibody was raised against the middle region of SFN
    Purification
    Affinity purified
    Immunogen
    SFN antibody was raised using the middle region of SFN corresponding to a region with amino acids FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLT
    Top Product
    Discover our top product SFN Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    SFN Blocking Peptide, catalog no. 33R-2923, is also available for use as a blocking control in assays to test for specificity of this SFN antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SFN antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Alternative Name
    SFN (SFN Products)
    Synonyms
    YWHAS antibody, Er antibody, Mme1 antibody, Ywhas antibody, stratifin antibody, SFN antibody, Sfn antibody
    Background
    SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
    Molecular Weight
    28 kDa (MW of target protein)
    Pathways
    p53 Signaling, Myometrial Relaxation and Contraction
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