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PTPN1 antibody (Middle Region)

PTPN1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN635198
  • Target See all PTPN1 Antibodies
    PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
    Binding Specificity
    • 16
    • 16
    • 13
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 103
    • 67
    • 49
    • 16
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 100
    • 7
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 96
    • 16
    Polyclonal
    Conjugate
    • 60
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPN1 antibody is un-conjugated
    Application
    • 80
    • 36
    • 25
    • 23
    • 15
    • 13
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificity
    PTPN1 antibody was raised against the middle region of PTPN1
    Purification
    Affinity purified
    Immunogen
    PTPN1 antibody was raised using the middle region of PTPN1 corresponding to a region with amino acids SGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVL
    Top Product
    Discover our top product PTPN1 Primary Antibody
  • Application Notes
    WB: 0.5 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PTPN1 Blocking Peptide, catalog no. 33R-8491, is also available for use as a blocking control in assays to test for specificity of this PTPN1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PTPN1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
    Alternative Name
    PTPN1 (PTPN1 Products)
    Synonyms
    PTPN1 antibody, PTP1B antibody, PTP-1B antibody, PTP-HA2 antibody, Ptp antibody, ptp1b antibody, wu:fk54h03 antibody, CPTP1 antibody, protein tyrosine phosphatase, non-receptor type 1 antibody, protein tyrosine phosphatase, non-receptor type 1 L homeolog antibody, PTPN1 antibody, Ptpn1 antibody, ptpn1 antibody, ptpn1.L antibody
    Background
    PTPN1 is the founding member of the protein tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
    Molecular Weight
    50 kDa (MW of target protein)
    Pathways
    TLR Signaling, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling
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