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Reticulon 4 antibody (Middle Region)

RTN4 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN635710
  • Target See all Reticulon 4 (RTN4) Antibodies
    Reticulon 4 (RTN4)
    Binding Specificity
    • 16
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 69
    • 49
    • 38
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 66
    • 3
    • 3
    • 2
    • 2
    Rabbit
    Clonality
    • 63
    • 13
    Polyclonal
    Conjugate
    • 36
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Reticulon 4 antibody is un-conjugated
    Application
    • 65
    • 28
    • 27
    • 21
    • 17
    • 17
    • 17
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    RTN4 antibody was raised against the middle region of RTN4
    Purification
    Affinity purified
    Immunogen
    RTN4 antibody was raised using the middle region of RTN4 corresponding to a region with amino acids RAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAV
    Top Product
    Discover our top product RTN4 Primary Antibody
  • Application Notes
    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    RTN4 Blocking Peptide, catalog no. 33R-7833, is also available for use as a blocking control in assays to test for specificity of this RTN4 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RTN4 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    Reticulon 4 (RTN4)
    Alternative Name
    RTN4 (RTN4 Products)
    Synonyms
    ASY antibody, NI220/250 antibody, NOGO antibody, NOGO-A antibody, NOGOC antibody, NSP antibody, NSP-CL antibody, Nbla00271 antibody, Nbla10545 antibody, Nogo-B antibody, Nogo-C antibody, RTN-X antibody, RTN4-A antibody, RTN4-B1 antibody, RTN4-B2 antibody, RTN4-C antibody, RTN4-Cw antibody, DKFZp459C0314 antibody, 1110020G17Rik antibody, AA407876 antibody, AA409940 antibody, AA960376 antibody, C130026I10Rik antibody, NgA antibody, Nogo-A antibody, mKIAA0886 antibody, mKIAA4153 antibody, NI-250 antibody, Nogo antibody, Vp20 antibody, r antibody, rat N antibody, rat NogoA antibody, reticulon-4 antibody, nogo antibody, rtn4 antibody, wu:fb17a02 antibody, wu:fb22f12 antibody, wu:fd61a07 antibody, zgc:92163 antibody, reticulon 4 antibody, reticulon 4a antibody, RTN4 antibody, rtn4 antibody, Rtn4 antibody, rtn4a antibody
    Background
    RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.
    Molecular Weight
    22 kDa (MW of target protein)
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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