MMP20 antibody (Middle Region)
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- Target See all MMP20 Antibodies
- MMP20 (Matrix Metalloproteinase 20 (MMP20))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MMP20 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- MMP20 antibody was raised against the middle region of MMP20
- Purification
- Affinity purified
- Immunogen
- MMP20 antibody was raised using the middle region of MMP20 corresponding to a region with amino acids AAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDA
- Top Product
- Discover our top product MMP20 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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MMP20 Blocking Peptide, catalog no. 33R-1063, is also available for use as a blocking control in assays to test for specificity of this MMP20 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MMP20 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- MMP20 (Matrix Metalloproteinase 20 (MMP20))
- Alternative Name
- MMP20 (MMP20 Products)
- Synonyms
- AI2A2 antibody, MMP-20 antibody, MMP25 antibody, MMP20 antibody, mmp20 antibody, matrix metallopeptidase 20 antibody, matrix metallopeptidase 20 L homeolog antibody, matrix metallopeptidase 20 (enamelysin) antibody, MMP20 antibody, mmp20.L antibody, Mmp20 antibody
- Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the Breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.
- Molecular Weight
- 43 kDa (MW of target protein)
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