SCN1B antibody

Catalog No. ABIN6389317

Product Details anti-SCN1B Antibody

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Unconjugated Rabbit polyclonal to SCN1B

Specificity: SCN1B Polyclonal Antibody detects endogenous levels of protein.

Purification: SCN1B antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Comment:

The overall expression of isoforms 1 and 2 is very similar. Isoform 1 is abundantly expressed in skeletal muscle, heart and brain. Isoform 2 is highly expressed in brain and skeletal muscle and present at a very low level in heart, placenta, lung, liver, kidney and pancreas. In brain, isoform 2 is most abundant in the cerebellum, followed by the cerebral cortex and occipital lobe, while isoform 1 levels are higher in the cortex compared to the cerebellum. Isoform 2 is expressed in many regions of the brain, including cerebellar Purkinje cells, cortex pyramidal neurons and many of the neuronal fibers throughout the brain (at protein level). Also detected in dorsal root ganglion, in fibers of the spinal nerve and in cortical neurons and their processes (at protein level).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for SCN1B

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Alternative Name: SCN1B (SCN1B Products)

Synonyms: GEFSP1 antibody, sodium channel, voltage-gated, type I, beta antibody, sodium voltage-gated channel beta subunit 1 antibody, Scn1b antibody, SCN1B antibody

Molecular Weight: 23 kDa

Gene ID: 6324

UniProt: Q07699