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MCAM antibody (AA 161-189)

Name: MCAM antibody (AA 161-189)
SKU: ABIN650722
Price: 429 USD
Availability: InStock

MCAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB20606 unconjugated

Anti-MC Antibody (Center) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane.

Flow cytometric analysis of hela cells using MC Antibody (Center)(bottom histogr) compared to a negative control cell (top histogr)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

FACS

Formalin-fixed and paraffin-embedded human skin reacted with MC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

3 images

Catalog No. ABIN650722

Datasheet as PDF

Target See all MCAM Antibodies

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Binding Specificity
16

13

11

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 161-189
Reactivity
127

48

47

15

14

9

9

8

6

2
Human
Host
95

56

1

1

1

1
Rabbit
Compatible Secondaries
Clonality
86

69
Polyclonal
Conjugate
75

14

13

10

4

4

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MCAM antibody is un-conjugated
Application
91

71

66

44

20

20

17

12

12

5

4

4

3

3

2

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human MCAM.

Clone

RB20606

Isotype

Ig Fraction

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Application Notes

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Alternative Name

MCAM (MCAM Products)

Background

MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Molecular Weight

71607

Gene ID

4162

NCBI Accession

NP_006491

UniProt

P43121