ENPP2 antibody (AA 377-406)

Catalog No. ABIN650746

Product Details anti-ENPP2 Antibody

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Binding Specificity: AA 377-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the Central region of human ENPP2.

Clone: RB18117

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:2000. WB: 1:2000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Alternative Name: ENPP2 (ENPP2 Products)

Synonyms: ATX antibody, ATX-X antibody, AUTOTAXIN antibody, LysoPLD antibody, NPP2 antibody, PD-IALPHA antibody, PDNP2 antibody, Npps2 antibody, PD-Ialpha antibody, Pdnp2 antibody, MGC132047 antibody, atx antibody, zgc:63550 antibody, autotaxin antibody, enpp2 antibody, enpp2a antibody, enpp2b antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antibody, ENPP2 antibody, Enpp2 antibody, enpp2 antibody, enpp2.L antibody, enpp2.S antibody

Background: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.

Molecular Weight: 98994

Gene ID: 5168

NCBI Accession: NP_001035181, NP_001124335, NP_006200

UniProt: Q13822