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CYP7B1 antibody (AA 252-281)

CYP7B1 Reactivity: Human WB, IHC (p), IF, FACS Host: Rabbit Polyclonal RB17087 unconjugated
Catalog No. ABIN652732
  • Target See all CYP7B1 Antibodies
    CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 252-281
    Reactivity
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 3
    • 1
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP7B1 antibody is un-conjugated
    Application
    • 14
    • 10
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CYP7B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human CYP7B1.
    Clone
    RB17087
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
    Alternative Name
    CYP7B1 (CYP7B1 Products)
    Synonyms
    CYP7B1 antibody, CBAS3 antibody, CP7B antibody, SPG5A antibody, AW261589 antibody, D3Ertd552e antibody, hct-1 antibody, cytochrome P450 family 7 subfamily B member 1 antibody, cytochrome P450, family 7, subfamily B, polypeptide 1 antibody, cytochrome P450, family 7, subfamily b, polypeptide 1 antibody, CYP7B1 antibody, cyp7b1 antibody, Cyp7b1 antibody
    Background
    CYP7B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
    Molecular Weight
    58256
    Gene ID
    9420
    NCBI Accession
    NP_004811
    UniProt
    O75881
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling
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