Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
Pr, M, Pig, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This CYP51A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human CYP51A1.
CP51 antibody, CYP51 antibody, CYPL1 antibody, LDM antibody, P450-14DM antibody, P450L1 antibody, cyp51a1 antibody, cytochrome P450 family 51 subfamily A member 1 antibody, cytochrome P450, family 51, subfamily A, polypeptide 1 antibody, cytochrome P450 family 51 subfamily A member 1 L homeolog antibody, CYP51A1 antibody, cyp51a1 antibody, cyp51a1.L antibody
Background
CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.