SDPR antibody (AA 109-135)

Catalog No. ABIN653890

Product Details anti-SDPR Antibody

Target: SDPR (Serum Deprivation Response (SDPR))

Binding Specificity: AA 109-135

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDPR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human SDR.

Clone: RB15464

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SDPR antibody (ABIN653890)

Sharan, Zhu, Xie, Li, Tang, Tang, Zhang, Xia: "Down-regulation of miR-206 is associated with Hirschsprung disease and suppresses cell migration and proliferation in cell models." in: Scientific reports, Vol. 5, pp. 9302, (2015) (PubMed).

Target Details for SDPR

Target: SDPR (Serum Deprivation Response (SDPR))

Alternative Name: SDR (SDPR Products)

Synonyms: CAVIN2 antibody, PS-p68 antibody, SDR antibody, cavin-2 antibody, sdr antibody, MGC84112 antibody, sdprb antibody, wu:fb39c08 antibody, wu:fk90b02 antibody, zgc:92231 antibody, caveolae associated protein 2 antibody, caveolae associated 2 antibody, caveolae associated protein 2 S homeolog antibody, serum deprivation response antibody, caveolae associated protein 2b antibody, CAVIN2 antibody, Cavin2 antibody, cavin2.S antibody, SDPR antibody, cavin2b antibody

Background: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.

Molecular Weight: 47173

Gene ID: 8436

NCBI Accession: NP_004648

UniProt: O95810