CD109 antibody

Catalog No. ABIN6559811

Product Details anti-CD109 Antibody

Target: CD109

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD109 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody W7C5 recognizes CD109, an approximately 165 kDa GPI-anchored extracellular protein expressed mainly on various hematopoietic cells, activated T lymphoblasts, activated platelets, and endothelial cells.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: WERI-RB-1 retinoblastoma cell line

Clone: W7C5

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD109

Target: CD109

Alternative Name: CD109 (CD109 Products)

Synonyms: CPAMD7 antibody, RP11-525G3.1 antibody, CD109 antibody, 9930012E15Rik antibody, AI480638 antibody, GARP antibody, CD109 molecule antibody, CD109 antigen antibody, CD109 antibody, Cd109 antibody, cd109 antibody

Background: CD109 Molecule,CD109, also known as the Gov platelet alloantigen, is a GPI-anchored glycoprotein which localizes to the surface of platelets, activated T-cells, and endothelial cells, as well as of various hematopoietic cells and T cell lines. The protein binds to and negatively regulates signaling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. The Gov antigen system is involved in platelet transfusion reaction, posttransfusion purpura and in neonatal alloimmune thrombocytopenia.,CPAMD7, p180, r150, FLJ38569, GPA

Gene ID: 135228

UniProt: Q6YHK3

Pathways: Activated T Cell Proliferation