SERPINB5 antibody (AA 94-123)

Catalog No. ABIN656020

Product Details anti-SERPINB5 Antibody

Target: SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

Binding Specificity: AA 94-123

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.

Clone: RB18808

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SERPINB5 antibody (ABIN656020)

Zhang, Liu, Shi, Qiao, Zeng, Feng, Deng, Liu, Wu: "Maspin impairs the function of endothelial cells: an implying pathway of preeclampsia." in: BMC pregnancy and childbirth, Vol. 17, Issue 1, pp. 328, (2018) (PubMed).

Shi, Chen, Liu, Qiao, Liu, Gong, Li, Du, Liu, Tang, Cao, Wu: "Decitabine improves the clinical manifestations of rats with l-NAME-induced pre-eclampsia: a potential approach to studying pre-eclampsia." in: Hypertension in pregnancy, pp. 1-10, (2015) (PubMed).

Target Details for SERPINB5

Target: SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

Alternative Name: Maspin (SERPINB5 Products)

Synonyms: 1110036M19Rik antibody, AI462524 antibody, AI646751 antibody, Maspin antibody, PI-5 antibody, Spi7 antibody, ovalbumin antibody, PI5 antibody, maspin antibody, Pi5 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody, serpin family B member 5 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog antibody, Serpinb5 antibody, SERPINB5 antibody, serpinb5.S antibody

Background: SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Molecular Weight: 42100

Gene ID: 5268

NCBI Accession: NP_002630

UniProt: P36952

Pathways: p53 Signaling