Tumor Necrosis Factor antibody (Tumor Necrosis Factor alpha)

Details for Product anti-TNF Antibody No. ABIN6566556
Antigen
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LOC103694380
  • tnfa
Reactivity
Human, Mouse (Murine)
933
362
285
117
112
96
95
56
51
40
26
17
15
6
6
6
5
4
4
3
3
3
2
2
1
1
1
1
Host
Rabbit
675
485
78
48
10
6
6
5
2
2
2
2
Clonality
Polyclonal
Conjugate
This Tumor Necrosis Factor antibody is un-conjugated
160
71
35
27
20
11
11
11
11
11
11
11
11
11
11
11
11
11
9
8
7
7
7
7
7
3
2
2
2
2
2
2
1
Application
Western Blotting (WB)
652
618
419
389
244
126
118
87
71
69
63
59
32
26
26
19
18
16
14
9
8
8
7
6
6
6
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
Options
Immunogen Recombinant protein of human TNF
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name TNF alpha (TNF Antibody Abstract)
Background

Synonyms: APC1,APC1 protein,Cachectin,DIF,Differentiation inducing factor,Macrophage cytotoxic factor,Tnf,TNF superfamily,member 2,TNF,macrophage derived,TNF,monocyte derived,TNF-a,TNF-alpha,TNFA,TNFA,TNFSF2,Tumor necrosis factor alpha,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor Necrosis Factor,Membrane Form,Tumor necrosis factor,soluble form

Background: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Molecular Weight

Observed_MW: 28kDa

Calculated_MW: 25kDa

Gene ID 7124
UniProt P01375
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Tumor Necrosis Factor alpha (TNF) antibody (ABIN6566556) Western blot analysis of extracts of various cell lines, using TNF antibody.
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