RYR2 antibody (Ryanodine Receptor 2 (Cardiac))

Details for Product anti-RYR2 Antibody No. ABIN6566568
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
59
41
39
6
2
1
1
1
Host
Rabbit
58
2
Clonality
Polyclonal
Conjugate
This RYR2 antibody is un-conjugated
3
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
31
25
24
12
11
4
3
2
2
1
1
Options
Immunogen A synthetic peptide of human RYR2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name RYR2 (RYR2 Antibody Abstract)
Background

Synonyms: ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,hRYR-2,ryanodine receptor 2 (cardiac),Ryanodine receptor 2,RyR,RYR-2,RyR2,RYR2,Type 2 ryanodine receptor,VTSIP

Background: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Molecular Weight

Observed_MW: 500kDa

Calculated_MW: 564kDa/565kDa

Gene ID 6262
UniProt Q92736
Pathways Myometrial Relaxation and Contraction
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Ryanodine Receptor 2 (Cardiac) (RYR2) antibody (ABIN6566568) Western blot analysis of extracts of mouse heart, using RYR2 antibody.
Image no. 2 for anti-Ryanodine Receptor 2 (Cardiac) (RYR2) antibody (ABIN6566568) Immunohistochemistry of paraffin-embedded human placenta using RYR2 Antibody.