ATP1A1 antibody (ATPase, Na+/K+ Transporting, alpha 1 Polypeptide)

Details for Product anti-ATP1A1 Antibody No. ABIN6566631
Antigen
Reactivity
Human
129
123
97
12
12
11
11
10
3
2
2
1
1
1
1
Host
Rabbit
144
16
1
Clonality
Polyclonal
Conjugate
This ATP1A1 antibody is un-conjugated
6
4
4
4
4
4
4
3
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
123
58
45
29
19
16
11
10
5
5
1
1
Options
Immunogen Recombinant protein of human ATP1A1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name Na+/K+-ATPase alpha1 (ATP1A1 Antibody Abstract)
Background

Synonyms: A1A1,AT1A1,AT1A1,ATP1A1,Atpa-1,ATPase Na+/K+ transporting alpha 1 polypeptide,ATPase Na+/K+ transporting subunit alpha 1,BC010319,EC 3.6.3.9,MGC3285,MGC38419,MGC51750,Na K ATPase alpha A catalytic polypeptide,Na K ATPase catalytic subunit alpha A protein,Na(+)/K(+) ATPase 1,Na(+)/K(+) ATPase alpha-1 subunit,Na+,K+ ATPase alpha subunit,Na+/K+ ATPase alpha 1 subunit,Na+/K+ ATPase 1,Na,K ATPase alpha 1 subunit,Nkaa1b,Sodium potassium ATPase alpha 1 polypeptide,Sodium pump 1,Sodium pump subunit alpha-1,sodium-potassium ATPase catalytic subunit alpha-1,Sodium/potassium-transporting ATPase subunit alpha-1

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 113kDa

Calculated_MW: 74kDa/109kDa/112kDa/113kDa

Gene ID 476
UniProt P05023
Pathways Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process
Application Notes WB 1:500 - 1:1000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) antibody (ABIN6566631) Immunohistochemistry of paraffin-embedded human stomach using ATP1A1 antibody.
Image no. 2 for anti-ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) antibody (ABIN6566631) Western blot analysis of extracts of LO2 cells, using ATP1A1 Antibody.
Image no. 3 for anti-ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) antibody (ABIN6566631) Immunohistochemistry of paraffin-embedded human prostate using ATP1A1 antibody.