IL17A antibody (Interleukin 17A)

Details for Product anti-IL17A Antibody No. ABIN6566643
Antigen
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
158
80
30
4
4
3
3
2
2
Host
Rabbit
119
44
32
19
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
32
20
13
10
9
5
1
1
1
1
1
1
1
Application
Western Blotting (WB)
140
139
51
24
17
14
12
9
7
6
6
3
3
1
1
1
1
1
1
1
1
1
Options
Immunogen Recombinant protein of human IL17A
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name IL17A (IL17A Antibody Abstract)
Background

Synonyms: CTLA 8,CTLA-8,CTLA8,Cytotoxic T lymphocyte associated antigen 8,Cytotoxic T lymphocyte associated protein 8,Cytotoxic T lymphocyte associated serine esterase 8,Cytotoxic T-lymphocyte-associated antigen 8,IL 17A,IL-17,IL-17A,IL17,IL17,Il17a,Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8),Interleukin 17A,Interleukin-17A,Interleukin17,Interleukin17A,OTTHUMP00000016597,OTTMUSP00000046003

Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Molecular Weight

Observed_MW: 35kDa

Calculated_MW: 17kDa

Gene ID 3605
UniProt Q16552
Application Notes WB 1:200 - 1:500
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Interleukin 17A (IL17A) antibody (ABIN6566643) Western blot analysis of extracts of various cell lines, using IL17A antibody.