JAK3 antibody (Janus Kinase 3)

Details for Product anti-JAK3 Antibody No. ABIN6566668
Antigen
Reactivity
Human
136
79
59
2
2
2
2
2
1
Host
Rabbit
120
21
Clonality
Polyclonal
Conjugate
This JAK3 antibody is un-conjugated
10
7
7
7
7
7
7
5
4
2
2
2
2
2
1
1
1
Application
Western Blotting (WB)
74
54
29
23
17
14
12
8
4
3
3
3
1
1
Options
Immunogen A synthetic peptide of human JAK3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name JAK3 (JAK3 Antibody Abstract)
Background

Synonyms: EC 2.7.10.2,JAK 3,JAK L,JAK-3,Jak3,JAK3 HUMAN,JAK3,JAKL,Janus kinase 3 (a protein tyrosine kinase,leukocyte),Janus kinase 3,Janus Kinase3,L JAK,L-JAK,Leukocyte janus kinase,LJAK,Protein tyrosine kinase leukocyte,Tyrosine protein kinase JAK3,Tyrosine-protein kinase JAK3

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Molecular Weight

Observed_MW: 125kDa

Calculated_MW: 68kDa/121kDa/125kDa

Gene ID 3718
UniProt P52333
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded protein response
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Janus Kinase 3 (JAK3) antibody (ABIN6566668) Western blot analysis of extracts of U-87MG cells, using JAK3 antibody.