Interferon Regulatory Factor 3 (IRF3) antibody

Details for Product No. ABIN6566678
Antigen
Reactivity
Human, Mouse (Murine)
277
122
73
6
6
6
3
2
2
1
1
1
Host
Rabbit
271
33
2
Clonality
Polyclonal
Conjugate
Un-conjugated
12
8
8
8
8
8
8
6
6
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
235
125
88
53
48
26
19
17
15
14
8
6
5
3
2
2
2
Options
Immunogen Recombinant Protein of human IRF3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name IRF3 (IRF3 Antibody Abstract)
Background

Synonyms: IIAE7,Interferon regulatory factor 3,IRF 3,IRF-3,IRF3,IRF3,MGC94729

Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight

Observed_MW: 47kDa, 55kDa

Calculated_MW: 12kDa/16kDa/33kDa/47kDa/49kDa

Gene ID 3661
UniProt Q14653
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Interferon Regulatory Factor 3 (IRF3) antibody (ABIN6566678) Western blot analysis of extracts of various cell lines, using IRF3 antibody.