BIRC2 antibody (Baculoviral IAP Repeat Containing 2)

Details for Product anti-BIRC2 Antibody No. ABIN6566682
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
107
39
33
2
2
1
Host
Rabbit
105
4
Clonality
Polyclonal
Conjugate
This BIRC2 antibody is un-conjugated
7
6
3
2
2
2
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
101
49
35
20
9
8
4
4
3
2
1
1
Options
Immunogen Recombinant protein of human BIRC2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name BIRC2 (BIRC2 Antibody Abstract)
Background

Synonyms: API 1,API1,Apoptosis inhibitor 1,Baculoviral IAP repeat containing 2,Baculoviral IAP repeat containing protein 2,Baculoviral IAP repeat-containing protein 2,BIRC 2,BIRC2,BIRC2,C IAP1,C-IAP1,cIAP 1,cIAP1,HIAP 2,HIAP-2,HIAP2,IAP 2,IAP homolog B,IAP-2,IAP2,Inhibitor of apoptosis protein 2,MIHB,NFR2 TRAF signalling complex protein,RING finger protein 48,RNF 48,RNF48,TNFR2 TRAF signaling complex protein 2,TNFR2-TRAF-signaling complex protein 2

Background: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 69kDa

Calculated_MW: 64kDa/69kDa

Gene ID 329
UniProt Q13490
Pathways Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
Application Notes WB 1:500 - 1:2000 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Baculoviral IAP Repeat Containing 2 (BIRC2) antibody (ABIN6566682) Western blot analysis of extracts of various cell lines, using BIRC2 antibody.
Image no. 2 for anti-Baculoviral IAP Repeat Containing 2 (BIRC2) antibody (ABIN6566682) Immunofluorescence analysis of A549 cells using BIRC2 antibody.