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MSH6 antibody

MSH6 Reactivity: Human, Mouse, Monkey IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566722
  • Target See all MSH6 Antibodies
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reactivity
    • 78
    • 35
    • 29
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Monkey
    Host
    • 58
    • 17
    • 3
    Rabbit
    Clonality
    • 46
    • 32
    Polyclonal
    Conjugate
    • 46
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH6 antibody is un-conjugated
    Application
    • 53
    • 27
    • 25
    • 20
    • 14
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MSH6 (NP_000170.1).
    Isotype
    IgG
    Top Product
    Discover our top product MSH6 Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:20-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Alternative Name
    MSH6 (MSH6 Products)
    Synonyms
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    Background
    This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
    Molecular Weight

    Observed_MW: 160kDa

    Calculated_MW: 119kDa/120kDa/137kDa/152kDa

    Gene ID
    2956
    UniProt
    P52701
    Pathways
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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