Synonyms: bHLHb26,Cell growth inhibiting gene 8,class B basic helix loop helix protein 26,Class B basic helix-loop-helix protein 26,DNA binding protein inhibitor ID 2,DNA binding protein inhibitor ID2,DNA-binding protein inhibitor ID-2,GIG 8,GIG8,Helix loop helix protein ID2,ID2,ID2,ID2A,ID2H,Inhibitor of differentiation 2,Inhibitor of DNA binding 2,Inhibitor of DNA binding 2,dominant negative helix loop helix protein,MGC26389
Background: The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.