PCDH15 antibody (Protocadherin-15)

Details for Product anti-PCDH15 Antibody No. ABIN6566771
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
17
10
7
2
2
1
1
1
1
1
Host
Rabbit
15
3
2
Clonality
Polyclonal
Application
Western Blotting (WB)
17
7
5
4
4
3
2
2
1
1
1
Options
Immunogen Recombinant protein of human PCDH15
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PCDH15 (PCDH15 Antibody Abstract)
Background

Synonyms: Protocadherin Related 15,Cadherin-Related Family Member 15,USH1F,Deafness, Autosomal Recessive 23,Protocadherin 15,Protocadherin-15,CDHR15,DFNB23

Background: This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.

Molecular Weight

Observed_MW: 100kDa

Calculated_MW: 92kDa/106kDa/185kDa/197kDa/216kDa

Gene ID 65217
UniProt Q96QU1
Pathways Sensory Perception of Sound
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Protocadherin-15 (PCDH15) antibody (ABIN6566771) Western blot analysis of extracts of various cell lines, using PCDH15 antibody.