Synonyms: Bicarbonate transporter,BT,NBC2,NBC3,S4A7,SBC2,SLC4A6,Sodium bicarbonate cotransporter 2,Sodium bicarbonate cotransporter 2b,Sodium bicarbonate cotransporter 3,Solute carrier family 4 member 7,Solute carrier family 4 sodium bicarbonate cotransporter member 7
Background: This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.