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TYMS antibody

TYMS Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566932
  • Target See all TYMS Antibodies
    TYMS (Thymidylate Synthetase (TYMS))
    Reactivity
    • 92
    • 28
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 49
    • 41
    • 2
    Rabbit
    Clonality
    • 48
    • 44
    Polyclonal
    Conjugate
    • 46
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TYMS antibody is un-conjugated
    Application
    • 51
    • 42
    • 35
    • 22
    • 19
    • 19
    • 19
    • 17
    • 14
    • 13
    • 11
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TYMS (NP_001062.1).
    Isotype
    IgG
    Top Product
    Discover our top product TYMS Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TYMS (Thymidylate Synthetase (TYMS))
    Alternative Name
    TYMS (TYMS Products)
    Synonyms
    FN1 antibody, ECK2823 antibody, JW2795 antibody, ts antibody, Ts antibody, HST422 antibody, TMS antibody, TS antibody, thymidylate synthetase antibody, contains intron in T4 phage antibody, ThyE antibody, thymidylate synthase antibody, thymidylate synthetase L homeolog antibody, TYMS antibody, thyA antibody, td antibody, thyE antibody, DDA3937_RS04960 antibody, tyms.L antibody, XBJ1_RS15770 antibody, EAMY_RS20680 antibody, Tyms antibody
    Target Type
    Viral Protein
    Background
    Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
    Molecular Weight

    Observed_MW: 36kDa

    Calculated_MW: 26kDa/31kDa/35kDa

    Gene ID
    7298
    UniProt
    P04818
    Pathways
    Mitotic G1-G1/S Phases
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