MTAP antibody (Methylthioadenosine phosphorylase)

Details for Product anti-MTAP Antibody No. ABIN6566953
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
69
18
10
6
2
2
2
2
1
1
1
1
Host
Rabbit
62
9
Clonality
Polyclonal
Conjugate
This MTAP antibody is un-conjugated
5
4
3
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
59
36
18
11
10
6
6
5
4
2
2
2
1
1
1
Options
Immunogen Recombinant protein of human MTAP
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MTAP (MTAP Antibody Abstract)
Background

Synonyms: 5' methylthioadenosine phosphorylase,5''-methylthioadenosine phosphorylase,BDMF,c86fus,DMSFH,DMSMFH,Epididymis luminal protein 249,HEL 249,LGMBF,MeSAdo phosphorylase,Methylthioadenosine phosphorylase,MSAP,MTA phosphorylase,MTAP,MTAP,MTAPase,S methyl 5 thioadenosine phosphorylase,S methyl 5' thioadenosine phosphorylase,S-methyl-5''-thioadenosine phosphorylase

Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Molecular Weight

Observed_MW: 31kDa

Calculated_MW: 26kDa/30kDa/31kDa/32kDa/33kDa/36kDa/38kDa

Gene ID 4507
UniProt Q13126
Pathways Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Methylthioadenosine phosphorylase (MTAP) antibody (ABIN6566953) Western blot analysis of extracts of various cell lines, using MTAP antibody.
Image no. 2 for anti-Methylthioadenosine phosphorylase (MTAP) antibody (ABIN6566953) Immunohistochemistry of paraffin-embedded mouse liver using MTAP antibody.