LGR5 antibody (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5)

Details for Product anti-LGR5 Antibody No. ABIN6566975
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
167
65
29
1
1
Host
Rabbit
120
48
Clonality
Polyclonal
Conjugate
This LGR5 antibody is un-conjugated
5
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
119
48
37
30
30
25
14
3
3
2
1
1
1
Options
Immunogen Recombinant protein of human LGR5
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name LGR5 (LGR5 Antibody Abstract)
Background

Synonyms: FEX,G protein coupled receptor 49,G protein coupled receptor 67,g protein-coupled receptor fex,G-protein coupled receptor 49,G-protein coupled receptor 67,G-protein coupled receptor HG38,GPR 49,GPR 67,GPR49,GPR67,GRP 49,GRP49,HG 38,HG38,Leucine rich repeat containing G protein coupled receptor 5,Leucine-rich repeat-containing G-protein coupled receptor 5,LGR 5,LGR5,LGR5,MGC117008,Orphan G protein coupled receptor HG38

Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 105kDa

Calculated_MW: 92kDa/97kDa/99kDa

Gene ID 8549
UniProt O75473
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) antibody (ABIN6566975) Western blot analysis of extracts of various cell lines, using LGR5 antibody.