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MCM2 antibody (Minichromosome Maintenance Complex Component 2) Primary Antibody

MCM2 Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566984
$438.90
Plus shipping costs $45.00
200 μL ABIN6566984
200 μL ABIN6566984
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Target
    MCM2
    Reactivity
    Human, Mouse, Rat
    • 114
    • 63
    • 38
    • 10
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Host
    Rabbit
    • 117
    • 15
    • 1
    • 1
    Clonality
    Polyclonal
    • 119
    • 15
    Conjugate
    This MCM2 antibody is un-conjugated
    • 71
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    • 99
    • 58
    • 47
    • 29
    • 26
    • 21
    • 13
    • 12
    • 9
    • 8
    • 4
    • 4
    • 4
    • 3
    • 1
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human MCM2
    Isotype
    IgG
  • Application Notes
    WB 1:500 - 1:2000 IHC 1:100 - 1:200
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM2
    Alternative Name
    MCM2 (MCM2 Antibody Abstract)
    Synonyms
    CG7538, DmMCM2, DmMcm2, DmeMCM2, Dmel\\CG7538, MCM2, MCM2-7, MCM2_DROME, McM2, PCR3, dMCM2, l(3)rL074, XMcm2, bm28, ccnl1, cdc19, cdcl1, mitotin, cb737, chunp6905, BM28, CCNL1, CDCL1, D3S3194, MITOTIN, MCM7, AA959861, AW476101, Mcmd2, mKIAA0030, Minichromosome maintenance 2, minichromosome maintenance complex component 2, minichromosome maintenance complex component 2 L homeolog, Mcm2, mcm2, MCM2, mcm2.L
    Background

    Synonyms: BM28,CCNL 1,CCNL1,CDC like 1,cdc19,CDCL 1,CDCL1,Cell devision cycle like 1,Cyclin like 1,D3S3194,DNA replication licensing factor MCM2,KIAA0030,MCM 2,MCM2,MCM2 minichromosome maintenance deficient 2 mitotin,MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae),MCM2 minichromosome maintenance deficient 2,mitotin,MCM2,MGC10606,Minichromosome maintenance complex component 2,Minichromosome maintenance deficient 2 (mitotin),Minichromosome maintenance deficient 2 mitotin,Minichromosome maintenance protein 2,Minichromosome maintenance protein 2 homolog,Mitotin,Nuclear protein BM28,OTTHUMP00000216047,OTTHUMP00000216050

    Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

    Molecular Weight

    Observed_MW: 130kDa

    Calculated_MW: 101kDa

    Gene ID
    4171
    UniProt
    P49736
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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