FAM3B antibody

Catalog No. ABIN6567029

Product Details anti-FAM3B Antibody

Target: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM3B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human FAM3B (NP_478066.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200 IF 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM3B

Target: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Alternative Name: FAM3B (FAM3B Products)

Synonyms: 2-21 antibody, C21orf11 antibody, C21orf76 antibody, ORF9 antibody, PANDER antibody, 9030624C24Rik antibody, D16Jhu19e antibody, Pander antibody, RGD1311662 antibody, family with sequence similarity 3 member B antibody, family with sequence similarity 3, member B antibody, FAM3B antibody, Fam3b antibody

Target Type: Viral Protein

Background: FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78 % sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5 % of the human genome.

Molecular Weight:

Calculated_MW: 20kDa/25kDa/30kDa

Gene ID: 54097

UniProt: P58499

Pathways: Hormone Transport