Metabotropic Glutamate Receptor 1 antibody (Glutamate Receptor, Metabotropic 1)

Details for Product anti-GRM1 Antibody No. ABIN6567063
Antigen
Reactivity
Rat (Rattus)
158
95
81
2
2
1
1
1
1
1
Host
Rabbit
156
16
4
1
Clonality
Polyclonal
Conjugate
This Metabotropic Glutamate Receptor 1 antibody is un-conjugated
10
7
7
6
6
5
4
4
4
4
4
4
1
1
1
1
1
1
Application
Western Blotting (WB)
108
66
64
35
17
11
11
7
6
3
2
1
1
Options
Immunogen Recombinant protein of human GRM1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name GRM1 (GRM1 Antibody Abstract)
Background

Synonyms: Glutamate receptor metabotropic 1,glutamate receptor,metabotropic 1,GPRC1A,GRM1,GRM1-Alpha,GRM1,GRM1A,Metabotropic glutamate receptor 1,mGlu1,mGluR1,MGLUR1-Alpha,MGLUR1A,SCAR13

Background: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight

Observed_MW: 132kDa

Calculated_MW: 101kDa/132kDa

Gene ID 2911
UniProt Q13255
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Glutamate Receptor, Metabotropic 1 (GRM1) antibody (ABIN6567063) Western blot analysis of extracts of rat liver, using GRM1 antibody.