TJP3 antibody

Catalog No. ABIN6567766

Product Details anti-TJP3 Antibody

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human TJP3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TJP3

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Alternative Name: TJP3 (TJP3 Products)

Synonyms: cb766 antibody, wu:fj93c08 antibody, zo-3 antibody, zo3 antibody, ZO-3 antibody, ZO3 antibody, tight junction protein 3 antibody, tight junction protein 3 S homeolog antibody, tjp3 antibody, tjp3.S antibody, TJP3 antibody, Tjp3 antibody

Background:

Synonyms: Tight junction protein 3,Tight junction protein ZO-3,Tight junction protein ZO3,TJP3,ZO3,ZO3,Zona occludens protein 3,Zonula occludens protein 3

Background: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.

Molecular Weight:

Observed_MW: 115kDa

Calculated_MW: 97kDa/101kDa/102kDa/103kDa

Gene ID: 27134

UniProt: O95049