SCYL2 antibody

Catalog No. ABIN6567813

Product Details anti-SCYL2 Antibody

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SCYL2 (NP_060458.3).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2 (SCYL2 Products)

Synonyms: RGD1305665 antibody, CVAK104 antibody, AU015688 antibody, AW536445 antibody, BC030932 antibody, D10Ertd802e antibody, SCY1 like pseudokinase 2 antibody, SCY1-like protein 2 antibody, SCY1-like 2 (S. cerevisiae) antibody, Scyl2 antibody, SCYL2 antibody, LOC452160 antibody

Background: The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight:

Observed_MW: 99kDa

Calculated_MW: 103kDa

Gene ID: 55681

UniProt: Q6P3W7