MANF antibody
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- Target See all MANF Antibodies
- MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MANF antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human MANF
- Isotype
- IgG
- Top Product
- Discover our top product MANF Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
- Alternative Name
- MANF (MANF Products)
- Synonyms
- ARMET antibody, ARP antibody, 3230402M22Rik antibody, AA407711 antibody, AA408789 antibody, AA673178 antibody, Armet antibody, D17914 antibody, D18Mgi17 antibody, MANF antibody, RBM15B antibody, ARP-like antibody, CG7013 antibody, DmMANF antibody, Dmel\\CG7013 antibody, anon-EST:ParkEST188 antibody, arp antibody, armet antibody, im:6909481 antibody, zgc:153327 antibody, manf antibody, mesencephalic astrocyte derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor antibody, RNA binding motif protein 15B antibody, Mesencephalic astrocyte-derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor S homeolog antibody, MANF antibody, Manf antibody, RBM15B antibody, manf antibody, manf.S antibody
- Background
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Synonyms: Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,ARMET,ARMET protein,ARP,Manf,MANF,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,MGC142148,MGC142150,Protein ARMET
Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
- Molecular Weight
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Observed_MW: 16kDa
Calculated_MW: 20kDa
- Gene ID
- 7873
- UniProt
- P55145
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