PRAME antibody
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- Target See all PRAME Antibodies
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRAME antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PRAME
- Isotype
- IgG
- Top Product
- Discover our top product PRAME Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Alternative Name
- PRAME (PRAME Products)
- Synonyms
- PRAME antibody, CT130 antibody, MAPE antibody, OIP-4 antibody, OIP4 antibody, 4930534P07Rik antibody, preferentially expressed antigen in melanoma antibody, PRAME antibody, Prame antibody
- Background
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Synonyms: 4930534P07Rik,Cancer/testis antigen 130,CT130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,Opa interacting protein OIP4,OPA-interacting protein 4,PRAME,PRAME,Preferentially expressed antigen in melanoma ,Preferentially expressed antigen of melanoma,RP23-250F8.3
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 58kDa
Calculated_MW: 57kDa
- Gene ID
- 23532
- UniProt
- P78395
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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