DRD3 antibody

Catalog No. ABIN6568415

Product Details anti-DRD3 Antibody

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human DRD3 (NP_000787.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Alternative Name: DRD3 (DRD3 Products)

Synonyms: DRD3 antibody, D3R antibody, D3DR antibody, ETM1 antibody, FET1 antibody, dopamine receptor D3 antibody, drd3 antibody, DRD3 antibody, Drd3 antibody

Background: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Molecular Weight:

Observed_MW: 44kDa

Calculated_MW: 40kDa/44kDa

Gene ID: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity