PSMB7 antibody

Catalog No. ABIN6568470

Product Details anti-PSMB7 Antibody

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB7 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PSMB7 (NP_002790.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMB7

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Alternative Name: PSMB7 (PSMB7 Products)

Synonyms: DDBDRAFT_0185624 antibody, DDBDRAFT_0232933 antibody, DDB_0185624 antibody, DDB_0232933 antibody, AU020723 antibody, MC14 antibody, Z antibody, 20S proteasome subunit beta-7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antibody, proteasome subunit beta 7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 antibody, proteasome (prosome, macropain) subunit, beta type 7 antibody, psmB7 antibody, psmb7.S antibody, PSMB7 antibody, Psmb7 antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.

Molecular Weight:

Observed_MW: 30kDa

Calculated_MW: 15kDa/29kDa

Gene ID: 5695

UniProt: Q99436

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA