PTPRN2 antibody
-
- Target See all PTPRN2 Antibodies
- PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PTPRN2 antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PTPRN2 (NP_570858.2).
- Isotype
- IgG
- Top Product
- Discover our top product PTPRN2 Primary Antibody
-
-
- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))
- Alternative Name
- PTPRN2 (PTPRN2 Products)
- Synonyms
- IA-2beta antibody, IAR antibody, ICAAR antibody, PTPRP antibody, R-PTP-N2 antibody, 4930425H11Rik antibody, IA2beta antibody, PTP-NP antibody, Phol antibody, mKIAA0387 antibody, phogrin antibody, protein tyrosine phosphatase, receptor type N2 antibody, protein tyrosine phosphatase, receptor type, N polypeptide 2 antibody, PTPRN2 antibody, Ptprn2 antibody
- Background
- This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
- Molecular Weight
-
Observed_MW: 111kDa
Calculated_MW: 108kDa/109kDa/111kDa/114kDa
- Gene ID
- 5799
- UniProt
- Q92932
-