Unc5c antibody

Catalog No. ABIN6568481

Product Details anti-Unc5c Antibody

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Unc5c antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human UNC5C

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Unc5c

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Alternative Name: UNC5C (Unc5c Products)

Synonyms: UNC5C antibody, UNC5H3 antibody, 6030473H24 antibody, AI047720 antibody, B130051O18Rik antibody, Unc5h3 antibody, rcm antibody, wu:fb03d07 antibody, unc-5 netrin receptor C antibody, UNC5C antibody, Unc5c antibody, unc5c antibody

Background:

Synonyms: homolog of C. elegans transmembrane receptor Unc5 ,Netrin receptor UNC5C,Protein unc 5 homolog C,Protein unc-5 homolog 3,Protein unc-5 homolog C,Unc 5 homolog 3,Unc 5 homolog C,Unc5 (C.elegans homolog) c ,Unc5c,UNC5C,UNC5H3

Background: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin, they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

Molecular Weight:

Observed_MW: 103kDa

Calculated_MW: 66kDa/103kDa

Gene ID: 8633

UniProt: O95185