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SMG7 antibody

SMG7 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6568670
  • Target See all SMG7 Antibodies
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Reactivity
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMG7 antibody is un-conjugated
    Application
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SMG7 (NP_963863.2).
    Isotype
    IgG
    Top Product
    Discover our top product SMG7 Primary Antibody
  • Application Notes
    WB 1:200-1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Alternative Name
    SMG7 (SMG7 Products)
    Synonyms
    9430023P16Rik antibody, mKIAA0250 antibody, C1orf16 antibody, EST1C antibody, SGA56M antibody, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG7, nonsense mediated mRNA decay factor antibody, Smg7 antibody, SMG7 antibody
    Background
    SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight

    Observed_MW: 127kDa

    Calculated_MW: 122kDa/127kDa/131kDa

    Gene ID
    9887
    UniProt
    Q92540
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