NECAB3 antibody

Catalog No. ABIN6568730

Product Details anti-NECAB3 Antibody

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NECAB3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NECAB3

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NECAB3

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Alternative Name: NECAB3 (NECAB3 Products)

Synonyms: Apba2bp antibody, APBA2BP antibody, NECAB3 antibody, EFCBP3 antibody, NIP1 antibody, STIP3 antibody, SYTIP2 antibody, XB51 antibody, dJ63M2.4 antibody, dJ63M2.5 antibody, 2900010M17Rik antibody, AI853434 antibody, Nip1 antibody, N-terminal EF-hand calcium binding protein 3 antibody, Necab3 antibody, NECAB3 antibody

Background:

Synonyms: amyloid beta (A4) precursor protein binding,family A,member 2 binding protein,Amyloid beta A4 protein binding family A member 2 binding protein,Amyloid beta A4 protein-binding family A member 2-binding protein,APBA2BP,dJ63M2.4,dJ63M2.5,EFCBP3,N terminal EF hand calcium binding protein 3,N-terminal EF-hand calcium-binding protein 3,NECA3,NECAB3,Nek2 interacting protein 1,Nek2-interacting protein 1,Neuronal calcium binding protein 3,Neuronal calcium-binding protein 3,NIP1,STIP3,Synaptotagmin interacting protein 2,SYTIP2,X11L binding protein 51,X11L-binding protein 51,XB51

Background: The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 50kDa

Calculated_MW: 22kDa/40kDa/44kDa

Gene ID: 63941

UniProt: Q96P71