TFPI antibody

Catalog No. ABIN6568810

Product Details anti-TFPI Antibody

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFPI antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TFPI (NP_001027452.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TFPI

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Alternative Name: TFPI (TFPI Products)

Synonyms: EPI antibody, LACI antibody, TFI antibody, TFPI1 antibody, A630013F22Rik antibody, AW552122 antibody, TFPI antibody, si:dz44f8.1 antibody, tfpib antibody, wu:fb92g01 antibody, zgc:152844 antibody, zgc:158592 antibody, tissue factor pathway inhibitor antibody, tissue factor pathway inhibitor a antibody, TFPI antibody, Tfpi antibody, tfpia antibody

Background: This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Molecular Weight:

Observed_MW: 31kDa

Calculated_MW: 28kDa/35kDa

Gene ID: 7035

UniProt: P10646