PDE1B antibody
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- Target See all PDE1B Antibodies
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE1B antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PDE1B (NP_000915.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDE1B Primary Antibody
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- Application Notes
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
- Alternative Name
- PDE1B (PDE1B Products)
- Synonyms
- 63kDa antibody, Pde1b1 antibody, PDE1B1 antibody, PDES1B antibody, Aop2 antibody, phosphodiesterase 1B, Ca2+-calmodulin dependent antibody, phosphodiesterase 1B antibody, Pde1b antibody, PDE1B antibody
- Background
- The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
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Observed_MW: 59kDa
Calculated_MW: 59kDa/61kDa
- Gene ID
- 5153
- UniProt
- Q01064
- Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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