OPRL1 antibody

Catalog No. ABIN6569456

Product Details anti-OPRL1 Antibody

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human OPRL1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPRL1

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Alternative Name: OPRL1 (OPRL1 Products)

Synonyms: KOR-3 antibody, NOCIR antibody, OOR antibody, ORL1 antibody, KOR3 antibody, LC132 antibody, MOR-C antibody, OFQR antibody, Oprl antibody, XOR1 antibody, OPRL antibody, ORGC antibody, morc antibody, opioid related nociceptin receptor 1 antibody, opiate receptor-like 1 L homeolog antibody, opiate receptor-like 1 antibody, opioid receptor-like 1 antibody, OPRL1 antibody, oprl1.L antibody, LOC100335303 antibody, Oprl1 antibody

Background: The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molecular Weight:

Observed_MW: 50kDa

Calculated_MW: 40kDa

Gene ID: 4987

UniProt: P41146