CDK2AP1 antibody

Catalog No. ABIN6569649

Product Details anti-CDK2AP1 Antibody

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2AP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CDK2AP1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK2AP1

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Alternative Name: DOC1 (CDK2AP1 Products)

Synonyms: MGC64532 antibody, doc1 antibody, st19 antibody, doc-1 antibody, dorc1 antibody, p12doc-1 antibody, Apc10 antibody, Cdkap1 antibody, DORC1 antibody, Doc1 antibody, ST19 antibody, p12 antibody, DOC1 antibody, p12DOC-1 antibody, cyclin-dependent kinase 2 associated protein 1 S homeolog antibody, cyclin dependent kinase 2 associated protein 1 antibody, cyclin dependent kinase 2 associated protein 1 pseudogene antibody, cyclin-dependent kinase 2 associated protein 1 antibody, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antibody, cdk2ap1.S antibody, CDK2AP1 antibody, LOC475806 antibody, cdk2ap1 antibody, Cdk2ap1 antibody

Background:

Synonyms: CDK2 A1,CDK2 associated protein 1,CDK2-associated protein 1,CDK2AP1,CDKA1,CDKA1,Cyclin dependent kinase 2 associated protein 1,Cyclin-dependent kinase 2-associated protein 1,Deleted in oral cancer 1,DOC 1,DOC 1 related protein,DOC 1R,DOC-1,DOC1,DOC1R,DORC1,p12DOC 1,Putative oral cancer suppressor,ST19

Background: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight:

Observed_MW: 12kDa

Calculated_MW: 9kDa/12kDa

Gene ID: 8099

UniProt: O14519