TRIOBP antibody

Catalog No. ABIN6569705

Product Details anti-TRIOBP Antibody

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIOBP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human TRIOBP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIOBP (TRIOBP Products)

Synonyms: tara antibody, DFNB28 antibody, TARA antibody, dJ37E16.4 antibody, AI428493 antibody, EST478828 antibody, Tara antibody, mKIAA1662 antibody, TRIO and F-actin binding protein antibody, TRIO and F-actin-binding protein antibody, TRIO and F-actin binding protein L homeolog antibody, TRIO and F-actin binding protein-like antibody, TRIOBP antibody, LOC100354753 antibody, triobp.L antibody, TRIOBPL antibody, Triobp antibody

Background:

Synonyms: DFNB28,KIAA1662,Protein TARA,TARA,Tara like protein,TRIO and F actin binding protein,Trio and filamentous actin binding protein,Trio associated repeat on actin

Background: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Molecular Weight:

Observed_MW: 70kDa

Calculated_MW: 47kDa/68kDa/74kDa/125kDa/243kDa/250kDa/261kDa

Gene ID: 11078

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization