RNMTL1 antibody

Catalog No. ABIN6569757

Product Details anti-RNMTL1 Antibody

Target: RNMTL1 (RNA Methyltransferase Like 1 (RNMTL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNMTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MRM3 (NP_060616.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNMTL1

Target: RNMTL1 (RNA Methyltransferase Like 1 (RNMTL1))

Alternative Name: MRM3 (RNMTL1 Products)

Synonyms: 4833420N02Rik antibody, AI255153 antibody, HC90 antibody, RGD1309077 antibody, rnmtl1 antibody, zgc:112452 antibody, hm:zehn2050 antibody, rnmtl1-b antibody, mrm3 antibody, rnmtl1.L antibody, mitochondrial rRNA methyltransferase 3 antibody, RNA methyltransferase like 1a antibody, RNA methyltransferase like 1b antibody, mitochondrial rRNA methyltransferase 3 L homeolog antibody, Mrm3 antibody, MRM3 antibody, rnmtl1a antibody, rnmtl1b antibody, mrm3.L antibody

Background: Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 47kDa

Calculated_MW: 47kDa

Gene ID: 55178

UniProt: Q9HC36