PCDHA6 antibody

Catalog No. ABIN6569764

Product Details anti-PCDHA6 Antibody

Target: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA6 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PCDHA6 (NP_061732.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDHA6

Target: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Alternative Name: PCDHA6 (PCDHA6 Products)

Synonyms: CNR2 antibody, CNRN2 antibody, CNRS2 antibody, CRNR2 antibody, PCDH-ALPHA6 antibody, CNR antibody, Cnr2 antibody, Crnr2 antibody, rCNRv06 antibody, PCDHA3 antibody, PCDHA6 antibody, PCDHA7 antibody, PCDHA9 antibody, protocadherin alpha 6 antibody, PCDHA6 antibody, Pcdha6 antibody

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molecular Weight:

Observed_MW: 103kDa

Calculated_MW: 75kDa/86kDa/102kDa

Gene ID: 56142

UniProt: Q9UN73