HDAC8 antibody

Catalog No. ABIN6570142

Product Details anti-HDAC8 Antibody

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human HDAC8

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8 (HDAC8 Products)

Synonyms: HD8 antibody, CDLS5 antibody, HDACL1 antibody, MRXS6 antibody, RPD3 antibody, WTS antibody, 2610007D20Rik antibody, RGD1562895 antibody, wu:fd19a02 antibody, zgc:66196 antibody, ATHDA8 antibody, HDA8 antibody, HISTONE DEACETYLASE 8 antibody, T27G7.14 antibody, T27G7_14 antibody, histone deacetylase 8 antibody, histone deacetylase 8 antibody, histone deacetylase 8 L homeolog antibody, CC1G_05302 antibody, hdac8 antibody, HDAC8 antibody, Hdac8 antibody, hdac8.L antibody, HDA08 antibody

Background:

Synonyms: CDA07,CDLS5,HD 8,HD8,HDAC 8,Hdac8,HDAC8,HDACL 1,HDACL1,Histone deacetylase 8,Histone deacetylase like 1,MRXS6,RPD 3,RPD3,WTS

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 42kDa

Calculated_MW: 15kDa/16kDa/17kDa/28kDa/29kDa/31kDa/41kDa

Gene ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process