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Oncostatin M antibody

OSM Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570275
  • Target See all Oncostatin M (OSM) Antibodies
    Oncostatin M (OSM)
    Reactivity
    Human, Mouse, Rat
    Host
    • 60
    • 7
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 63
    • 7
    Polyclonal
    Conjugate
    • 37
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Oncostatin M antibody is un-conjugated
    Application
    • 56
    • 31
    • 13
    • 13
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human OSM (NP_065391.1).
    Isotype
    IgG
    Top Product
    Discover our top product OSM Primary Antibody
  • Application Notes
    IHC 1:50-1:100 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Oncostatin M (OSM)
    Alternative Name
    OSM (OSM Products)
    Synonyms
    OSM antibody, OncoM antibody, oncostatin M antibody, OSM antibody, Osm antibody
    Background
    This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Molecular Weight

    Observed_MW: 28kDa

    Calculated_MW: 28kDa

    Gene ID
    5008
    UniProt
    P13725
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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