CYP2C9 antibody

Catalog No. ABIN6570291

Product Details anti-CYP2C9 Antibody

Target: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2C9 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CYP2C9 (NP_000762.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP2C9

Target: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Alternative Name: CYP2C9 (CYP2C9 Products)

Synonyms: CPC9 antibody, CYP2C antibody, CYP2C10 antibody, CYPIIC9 antibody, P450IIC9 antibody, cytochrome P450 family 2 subfamily C member 9 antibody, CYP2C9 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Molecular Weight:

Observed_MW: 63kDa

Calculated_MW: 18kDa/55kDa

Gene ID: 1559

UniProt: P11712