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MMP2 antibody

MMP2 Reactivity: Human, Rat, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570309
  • Target See all MMP2 Antibodies
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Reactivity
    • 152
    • 80
    • 65
    • 49
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 125
    • 42
    • 1
    Rabbit
    Clonality
    • 122
    • 46
    Polyclonal
    Conjugate
    • 81
    • 14
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP2 antibody is un-conjugated
    Application
    • 136
    • 59
    • 52
    • 39
    • 39
    • 37
    • 31
    • 29
    • 18
    • 15
    • 14
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MMP2 (NP_004521.1).
    Isotype
    IgG
    Top Product
    Discover our top product MMP2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Alternative Name
    MMP2 (MMP2 Products)
    Synonyms
    2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody
    Background
    This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight

    Observed_MW: 75kDa

    Calculated_MW: 65kDa/68kDa/73kDa

    Gene ID
    4313
    UniProt
    P08253
    Pathways
    Activation of Innate immune Response
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